Jitendra Narayan
Scientist-E |
Decision Unit 1: Genomics and Genome Biology
Professor |
Academy of Scientific and Innovative Research
Within the broad domain of bioinformatics and computational biology, Jitendra Narayan's lab mainly focuses on chromosomal breakpoints, horizontal transfer of genes and genome evolution. His lab has developed computational pipelines and algorithms to harness biological data from genomes, epigenomes, transcriptomes, and proteomes.
Specific Interests
- Horizontal gene transfer (HGT)
- Genome Evolution
- DNA breaks and repair
His lab works on bdelloid rotifers, which are tolerant to extreme stresses including radiation, desiccation, and freezing. Understanding their survival mechanisms helps reveal how organisms repair genomes under stress. The lab is assembling rotifer genomes at chromosome level to study adaptation, development, and evolution.
Selected Publications
All Citations →- From bench to bedside: potential of translational research in COVID-19 and beyond. Shukla N, Shamim U, Agarwal P, Pandey R, Narayan J. Brief Funct Genomics. 2023 Nov 20:elad051.
- LncRNAs harbouring regulatory motifs within repeat elements modulate immune response towards COVID-19 disease severity and clinical outcomes. Chattopadhyay P, Mishra P, Khare K, Yadav A, Mehta P, Saifi S, Swaminathan A, Devi P, Parveen S, Tyagi A, Jha V, Tarai B, Jha S, Budhiraja S, Narayan J, Pandey R. Clin Transl Med. 2022 Jul;12(7):e932.
- Chromosome-level genome assembly reveals homologous chromosomes and recombination in asexual rotifer Adineta vaga. P Simion, J Narayan, A Houtain, A Derzelle, L Baudry, E Nicolas, R Arora,… Science Advances 2021 Oct 8;7(41):eabg4216.
- Comparative genomics reveals insights into avian genome evolution and adaptation. G Zhang, C Li, Q Li, B Li, DM Larkin, C Lee, JF Storz, A Antunes,… J Narayan… Science. 2014 Dec 12;346(6215):1311–20.
- Analyses of pig genomes provide insight into porcine demography and evolution. MAM Groenen, AL Archibald, H Uenishi, CK Tuggle, Y Takeuchi,… Narayan J,… Nature. 2012 Nov 15;491(7424):393–8.