Functional Genomics
Mohammed Faruq
Scientist-G |
Decision Unit 1: Genomics and Genome Biology
Professor |
Academy of Scientific and Innovative Research
Mohammed Faruq transitioned from medicine to genomics to study the genetic and molecular basis of movement disorders, particularly ataxia and other neurological diseases.
His lab collaborates with clinicians and researchers across India and internationally. It has conducted extensive genetic characterization of spinocerebellar ataxia using next-generation sequencing and is evolving toward studying molecular causality using patient-derived neuronal cell models.
Selected Publications
All Citations →- Generation and characterization of two human iPSC lines, IGIBi014-A and IGIBi015-A, from Friedreich's ataxia (FRDA) patients with pathogenic (GAA/TTC)n repeat expansion in first intron of the Frataxin (FXN) gene. Ahmad I, Kapoor H, Kumar Srivastava A, Faruq M. Stem Cell Res. 2023 Dec 16;74:103289.
- Childhood onset myoclonus-dystonia associated with a novel KCTD17 variant in an Indian patient. Garg D, Kapoor H, Ahmad I, Aroosa M, Agarwal A, Srivastava AK, Faruq M. Parkinsonism Relat Disord. 2023 Dec;117:105925.
- Investigation of RFC1 tandem nucleotide repeat locus in diverse neurodegenerative outcomes in an Indian cohort. Tyagi N, Uppili B, Sharma P, Parveen S, Saifi S, Jain A, Sonakar A, Ahmed I, Sahni S, Shamim U, Anand A, Suroliya V, Asokachandran V, Srivastava A, Sivasubbu S, Scaria V, Faruq M. Neurogenetics. 2023 Nov 2.
- Sequencing through hyperexpanded Friedreich's ataxia-GAA repeats by nanopore technology: implications in genotype-phenotype correlation. Uppili B, Sharma P, Ahmad I, Sahni S, Asokachandran V, Nagaraja AB, Srivastava AK, Faruq M. Brain Commun. 2023 Mar 29;5(2):fcad020.
- Generation of two induced pluripotent stem cell (iPSC) lines from patients with Duchenne muscular dystrophy (IGIBi006-A and IGIBi008-A) carrying exonic deletions in the dystrophin gene. Ahmad I, Goel D, Ghosh A, Kapoor H, Kumar D, Ramesh K, Ashley B, Deepika K, Shastry A, Faruq M. Stem Cell Res. 2022 Oct;64:102927.